https://leelabvirus.host/useful-links daily 0.75 2019-09-19 https://leelabvirus.host/covid19 daily 0.75 2022-01-17 https://leelabvirus.host/covid19/breaking-down-the-biology-behind-covid-19-therapies-and-antibody-testing monthly 0.5 2020-05-15 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1588966484918-RHG1EI52LA569RRJJHOP/F1.large.jpg COVID-19 Communication - Breaking Down the Biology Behind COVID-19 Therapeutics Possible targets for antivirals in the coronavirus life cycle. Image source: https://science.sciencemag.org/content/early/2020/05/07/science.abb9332/tab-figures-data https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1588900302530-Y0ULKA12KY9PHURXKPE9/image+2.png COVID-19 Communication - Breaking Down the Biology Behind COVID-19 Therapeutics Illustration of the delicate balance of immune system function. Image source: Drug Discovery World https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1588902142083-GPCR0HGT17QVS14MZSAC/image+3.png COVID-19 Communication - Breaking Down the Biology Behind COVID-19 Therapeutics How convalescent plasma transfer works. Image source: Johns Hopkins University https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1588903618432-Y92CW6GODQGAIFWYOM89/image+7.png COVID-19 Communication - Breaking Down the Biology Behind COVID-19 Therapeutics - Stephanie Schell, PhD Stephanie received her PhD in Virology and Immunology from the Penn State College of Medicine in 2019. For her PhD, she studied B cell and antibody responses induced after immunization and in the autoimmune disease, lupus. She is currently a postdoctoral scholar at the Penn State College of Medicine, working on several translational projects that focus on inflammatory skin diseases. When she isn’t in the lab, Stephanie enjoys being outside and competing in sports. https://leelabvirus.host/covid19/breaking-down-the-biology-part-2 monthly 0.5 2020-05-09 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1589044552513-X62P4XW25XXP0ZU7VM93/image+4.png COVID-19 Communication - Breaking down the biology behind antibodies and COVID-19 Antibody structure. The grey portion binds very specifically to the antigen (in our case, virus protein) against which it was raised. Image source: genome.gov https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1589046202426-TS47JIPWDI2WZKOHCHVD/image+5.png COVID-19 Communication - Breaking down the biology behind antibodies and COVID-19 The timeline and magnitude of antibody responses following infection. Image source: Biology-forums.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1589046601985-J4VJ38DJV5V9MXSBSCF9/image+6.png COVID-19 Communication - Breaking down the biology behind antibodies and COVID-19 Factors that affect immune responses. Image source: From Aguirre-Gamboa et al. Cell Reports 2016 Nov 22; 17(9): 2474–2487 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1589047381830-L77F28VJT4IPQK07DBQG/image+7.png COVID-19 Communication - Breaking down the biology behind antibodies and COVID-19 - Stephanie Schell, PhD Stephanie received her PhD in Virology and Immunology from the Penn State College of Medicine in 2019. For her PhD, she studied B cell and antibody responses induced after immunization and in the autoimmune disease, lupus. She is currently a postdoctoral scholar at the Penn State College of Medicine, working on several translational projects that focus on inflammatory skin diseases. When she isn’t in the lab, Stephanie enjoys being outside and competing in sports. https://leelabvirus.host/covid19/origins-part3 monthly 0.5 2020-04-13 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586138117701-EVS2HJI91HKKUF866OX4/edit1.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 A Centers for Disease Control and Prevention (CDC) scientist demonstrates a lab technique called “candling,” which determines if an egg is suitable for use in growing viruses. Photographer James Gathany. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586128631475-67YJPYSXYNKE5NGALIWL/Screen+Shot+2020-04-05+at+7.16.51+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 Top: the intermediate horseshoe bat, courtesy of mammalwatching.com Bottom: the Malayan pangolin; Firdia Lisnawati: AP Photo https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586129118450-72O5YZTU6JAIDFGS2O3Z/Screen+Shot+2020-04-05+at+7.25.01+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586216060703-HGFNMEUZSSQTX2HQ9R1M/Screen+Shot+2020-04-06+at+7.34.09+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 Closure of the Huanan Seafood Wholesale Market on January 1st, 2020. Photo: AFP https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586222261828-EW4M4U91JPGZE00JW1QS/Screen+Shot+2020-04-06+at+9.17.13+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586232745897-MX9OWGIZI1N1T2Q4VYTI/Wuhan_Institute_of_Virology_logo.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586364029976-IHCAZIEDLPWAFNADQLZ3/23795084-7922379-image-a-8_1579817036564.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 Map courtesy of The Daily Mail https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586364439488-31I687RULS7XFG38UFBH/Screen+Shot+2020-04-08+at+12.47.00+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 The, now withdrawn, pre-print even temporarily concerned NYT Op-Ed writer Ross Douthat. It shows the importance of waiting for peer review before jumping to conclusions. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586365138018-PJ1RRQVARF4Q9GH352RA/Screen+Shot+2020-03-23+at+1.39.51+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586365150919-11WKASHMZ0026VQL0LYF/Screen+Shot+2020-03-23+at+1.40.30+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586365150047-K1DAFONAE6RBIYSO4HMJ/Screen+Shot+2020-03-23+at+1.42.51+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586365129357-OJ10T8P025EPXL5JHN70/Screen+Shot+2020-03-23+at+1.37.21+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 3 https://leelabvirus.host/covid19/where-is-the-vaccine monthly 0.5 2020-04-06 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586051462286-N7E0MJAYISJ04DQ0H7RJ/48545839516_40835b3f4a_k.jpg COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 Toddler about to receive a vaccine from a doctor. Credit: Photographer: Heather Hazzan; Wardrobe: Ronald Burton; Props: Campbell Pearson; Hair: Hide Suzuki; Makeup: Deanna Melluso at See Management. Shot on location at One Medical. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586123486916-O6EQZGJ0IIV1CYLT12DY/image-asset.gif COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586103121394-5U56QLFIWZOS410EAL40/coronavirus.png COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586116700660-SSS9O41ZEFPYCIP6CRYM/COVID19_Timeline_SynBioBeta_LeapsByBayer-page-001.jpg COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586116818508-AALI3HDQDUMBPEUJJO87/VaccineTL04.jpg COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586103772951-490VDQ7PB6V11EXDJAM8/48546003607_9ee3a2b98f_o.jpg COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 Closeup of a doctor’s hand, vaccine, and arm. Photographer: Heather Hazzan; Wardrobe: Ronald Burton; Props: Campbell Pearson; Hair: Hide Suzuki; Makeup: Deanna Melluso at See Management. Shot on location at One Medical. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586131784013-HWQW9JXJRL2528UFQHMC/Picture1.jpg COVID-19 Communication - Where is the SARS-CoV-2 vaccine, anyways? Part 1 - Phil Domeier, PhD Phillip received his PhD in Virology and Immunology from Penn State College of Medicine in 2018, where he studied the immunological factors that promote pathogenic antibody production in Systemic Lupus Erythematosus (SLE). He is currently a postdoctoral fellow in the Ziegler Laboratory at the Benaroya Research Institute in Seattle, Washington. His current research aims to determine how genetic and environmental factors influence antibody production in patients with allergies and autoimmunity. Outside of the lab, Phillip enjoys snowboarding and hiking with his dog, Milo. https://leelabvirus.host/covid19/sars-cov-2-and-the-flu monthly 0.5 2020-04-03 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585766634600-9275DOU4AMPVN9OK2613/ah+choo.jpg COVID-19 Communication - How similar is SARS-CoV-2 to Influenza: A wolf in sheep’s clothing Image credit: https://blog.watsonconsoles.com/3-steps-help-psaps-beat-cold-and-flu-call-outs https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585767202084-1O9E7W2AHXMXOOARUZBK/2-take-preventative-flu.jpg COVID-19 Communication - How similar is SARS-CoV-2 to Influenza: A wolf in sheep’s clothing Image: https://www.cdc.gov/flu/prevent/preventing.html https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585767845160-OUSTOY7YGM7RXLSXA1XC/flu+vs+corona.png COVID-19 Communication - How similar is SARS-CoV-2 to Influenza: A wolf in sheep’s clothing Image made by Praneet Sanhu https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585836351137-SEM9V4C0G1JPGZOY0DYF/vox+image.png COVID-19 Communication - How similar is SARS-CoV-2 to Influenza: A wolf in sheep’s clothing https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585836625393-HJZC64LP2GQ6O5TNYRIZ/praneet.jpg COVID-19 Communication - How similar is SARS-CoV-2 to Influenza: A wolf in sheep’s clothing - Praneet Sandhu Praneet is currently a PhD student at Penn State College of Medicine in Hershey, PA. A virologist by chance, Praneet studies how cellular proteins are manipulated by human cytomegalovirus, a herpesvirus, for its own benefit. She is very interested in learning how viruses have figured out multiple ways to overcome host defenses. Outside of science, she likes to read about evolution and world history, and bake with her husband. https://leelabvirus.host/covid19/debunking-the-disinformation-a-case-study-for-covid19 monthly 0.5 2020-03-31 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585676144419-ZA3JI7STDJXGLQ8MDSHH/Debunked.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 Image courtesy of DLPNG.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585676284569-Y28K5CVJPWC2B1RM6CGS/disinformation.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585676512049-I0G6FEWKPGKCW939LBF6/90870565_521966641839512_7075522702454292480_n.jpg COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 An example of misinformation about COVID19. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585676875337-ZPPXTIKFTPABO6PJMGTK/Screen+Shot+2020-03-30+at+8.50.26+PM.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585677032823-YQCYSSY5P340KAK1OFGP/Ph+scale.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585677780983-X35JWV0FZZEXCEK6SH1I/pH+comparison.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585677966878-OARNCZGM2QB4GPHYQ0AV/Fusion_endosome.jpg COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585678393368-LTVWROLNFALASMNFNESZ/sickness.png COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585679636431-S7F2D3G3GLM90E1N9ZLV/1688068F-6274-4AF9-AD8B-68AF58BDF247.jpeg COVID-19 Communication - Debunking the Disinformation: A Case Study for COVID19 - Jillian Carmichael, PhD Jillian received her PhD in Virology from Penn State’s College of Medicine in 2019, where she studied molecular mechanisms of Herpes Simplex Virus spread. She is currently a postdoctoral fellow in the Lee lab at Mount Sinai. As the lone herpesvirologist in a paramyxovirus lab, Jillian is working to develop new methods to manipulate the Human Cytomegalovirus (HCMV) genome to better understand its cellular tropism and latency. When she’s not in the lab (or WFH during the pandemic), Jillian spends her time parenting her two young kids in NYC. Sometimes she runs for fun, but mostly she chases after her kiddos. Twitter: @ViralCarmichael https://leelabvirus.host/covid19/asymptomatic-transmission-age-and-covid19 monthly 0.5 2020-04-09 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585452316931-XGY5UDJU3KHHJR8KQOSK/Social_Distancing_Subway_Example_Gif.gif COVID-19 Communication - Asymptomatic transmission, age, and COVID19 Visual representation of how viral shedding facilitates transmission in public spaces; such transmission events can be decreased with stringent social distancing. GIF courtesy of Griffin Haas. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585446065582-WWMLWKLXTIH7HJTF2PE2/Pic+GH.png COVID-19 Communication - Asymptomatic transmission, age, and COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522122043-QTW0E7E2U9UQRDH4UE6J/CDC_Covid19_Social_Distancing_Tweet.png COVID-19 Communication - Asymptomatic transmission, age, and COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585525129012-UZIQ9K8CRO6DEC3OITHL/Covid-19-Transmission-graphic-01.gif COVID-19 Communication - Asymptomatic transmission, age, and COVID19 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585446343597-FMS4Z6W27GYG24KXD3X6/GH.png COVID-19 Communication - Asymptomatic transmission, age, and COVID19 - Griffin Haas Griffin is a PhD Student at the Icahn School of Medicine at Mount Sinai who received his B.S. in biology from Duke University. Griffin joined the Benhur Lee lab in 2020 and has since been involved in projects related to henipavirus/host protein-protein interactions. He is highly interested in emerging pathogens and how such viruses interact with their hosts during infection. Griffin is also interested in exploring ways to creatively visualize biological processes and enjoys generating graphics related to microbiology and infectious diseases. Email: griffin.haas@icahn.mssm.edu Twitter: @GriffinHaas https://leelabvirus.host/covid19/origins-part2 monthly 0.5 2020-04-11 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585246559831-LDXHVLMLOH0BBW7RVMR1/covid-19-pneumonia-12.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585257743026-22I88WSCY8411O2NQBG2/Screen+Shot+2020-03-26+at+5.21.55+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023942491-AZ3SNMT8GQPZFCEN0O7K/Screen+Shot+2020-03-24+at+12.25.18+AM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 Here we see “R” which indicates the monobasic cleavage site and “R X R/K R” which indicates the polybasic cleavage site. Blue stars indicate what tissues can be infected (modified from Han et al. 2020). https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585299424299-6S5OG0FACTXYG0D17RWV/ab_best.gif COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584997212332-95BGNKYV8C3RE8PTU0TY/Screen+Shot+2020-03-23+at+4.59.45+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 2 https://leelabvirus.host/covid19/why-are-we-so-worried-about-a-virus-that-has-only-killed-19000-people-worldwide monthly 0.5 2020-04-09 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104034506-15YXI2ZC4ATSZNL41JV5/Screen+Shot+2020-03-24+at+10.40.09+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104225085-PQRAV1PWXNAS0ES8ISD8/Screen+Shot+2020-03-24+at+10.43.33+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104316489-GJ318ROHPURNL1789VQN/Screen+Shot+2020-03-24+at+10.45.06+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104476304-K8EIM42R56FRD5GCIUXY/Screen%2BShot%2B2020-03-24%2Bat%2B10.46.48%2BPM.jpg COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104537244-EQ20RRFS85OR2F5N84GG/Screen+Shot+2020-03-24+at+10.48.48+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104670141-849SK7GFCILTKTH32V98/Screen+Shot+2020-03-24+at+10.50.58+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105358541-4KM6BFPRO6538OQUWRAY/Screen+Shot+2020-03-24+at+11.02.27+PM.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105600369-TBP2L7D36F1X4FY0X0Q5/F1.large.jpg COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585142850801-CYIY41BXT1JRT26CP2M9/Picture1.png COVID-19 Communication - Why are we so worried about a virus that’s ‘only’ killed 21,000 people worldwide? - Rachel Temple, PhD Rachel received her PhD in virology from Pennsylvania State University. She then went on to a post doctorate in Dr. Joshua Obar’s lab at Dartmouth College. In Dr. Obar’s lab, Rachel studied the immune response to influenza virus infection and how comorbidities such as asthma, can increase the severity of disease. Now Rachel works with STEMCELL TECHNOLOGIES in the Philadelphia area. https://leelabvirus.host/covid19/origins-part1 monthly 0.5 2020-04-11 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584984626945-FFELXU3VT646FCG8E40C/2010-Intermediate-Horseshoe-Bat-1024x676.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 Image courtesy of MammalWatching.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584986548814-HRTGVVEMAI5YXJ0431KI/zoonotic2.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988142239-VH8LLWFDQM8AH1R6N7ZB/Viral+Mutations.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988143172-8LKM0JS52PHKRERARSGB/selection.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989033799-GFRYRUXLV9FN4NRY13FJ/sars_newsweek.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989040386-FEYZMFKRF5NQH5CBKJCJ/Screen+Shot+2020-03-23+at+2.42.38+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990027373-WTIBJ6VFCQBXS8YLM338/Malay_civet.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 This is a civet cat, the presumed intermediate host between bats and humans for the original 2003 SARS outbreak. Courtesy of Kalyan Varma and Wikimedia Commons. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990717390-E3RA549S7J5JQQBVP5A3/khan_phylogenetic+tree.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 A phylogenetic tree illustration, courtesy of Khan Academy https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992147215-RSMARYIUHZUHJH2TDZY0/Screen+Shot+2020-03-23+at+3.35.09+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992538565-QHLAAUB5IP35NEJ2YF3W/Genomic+Organization+of+SARS-CoV-2.jpeg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 A visual representation of the SARS-CoV-2 genome, courtesy of Biorender. We can see the 3D structure of the spike protein and highlighted is a particular region called the receptor binding domain (RBD). It is shown bound to the human surface protein, ACE2. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585063152777-ILCDN87BI91YRX8GGXXO/likeness_genome.jpeg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065252768-7MSQQZER470JNK591X3K/spike.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065273090-CZLEHN1VJ4P2L9EQS0H4/SpikeProtein.jpeg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023704320-NLVUOZV4J0H9F2ANAS35/pangolin.jpg COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 Firdia Lisnawati: AP Photo; image of a Malayan pangolin https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023745812-SHGOORJLDOVIC7BFPSJI/Screen+Shot+2020-03-23+at+4.05.16+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 Figure altered from Xiao et al. 2020 https://doi.org/10.1101/2020.02.17.951335. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Communication - The Origins of SARS-CoV-2: Part 1 https://leelabvirus.host/covid19/introduction-to-sars-cov2-the-novel-coronavirus-that-causes-covid-19-illness monthly 0.5 2020-04-09 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584666660465-O2GUPA4RDH90B4CL8TNE/https%3A%2F%2Fwww.biorxiv.org%2Fcontent%2F10.1101%2F2020.03.02.972935v2.full COVID-19 Communication - Introduction to SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584673141982-DHTJD5N8JDO0QM64JKRR/Respiratory+Virus+Infection+Cycle.png COVID-19 Communication - Introduction to SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584896205948-J58T86C35UBCG95VH42J/https%3A%2F%2Fthespinoff.co.nz%2Fpolitics%2F22-03-2020%2Fsiouxsie-wiles-toby-morris-what-does-level-two-mean-and-why-does-it-matter%2F COVID-19 Communication - Introduction to SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584897615626-ZJ1UVYTAUL5MZ8BINIFZ/https%3A%2F%2Fthespinoff.co.nz%2Fsociety%2F09-03-2020%2Fthe-three-phases-of-covid-19-and-how-we-can-make-it-manageable%2F COVID-19 Communication - Introduction to SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584822128960-HP5N4F2GV7YNBOW6ED2G/Smokey-COVID-19.jpg COVID-19 Communication - Introduction to SARS-CoV2: Not a direct quote. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584823047493-1HK1B02QOY1UPOQZK8AS/social-distancing-infograph-eng-1.png COVID-19 Communication - Introduction to SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584914534681-5HZW7FMKAZDY8J8FJ95K/PHOTO-2020-03-22-17-44-28.jpg COVID-19 Communication - Introduction to SARS-CoV2: - Patricia Thibault, PhD Patricia hails from Canada and received her PhD from the University of Saskatchewan in 2014, where she studied Hepatitis C Virus (HCV). From 2014-2020 she was a postdoctoral fellow in Dr Benhur Lee’s lab at Mount Sinai where she studied a wide variety of paramyxoviruses. She is currently a research assistant in Dr. Michael C. Levin’s lab in the Department of Anatomy, Physiology, and Pharmacology in the College of Medicine at the University of Saskatchewan. Twitter: @escape_mutant https://leelabvirus.host/covid19-japanese daily 0.75 2020-04-03 https://leelabvirus.host/covid19-japanese/origins-part2 monthly 0.5 2020-04-03 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585246559831-LDXHVLMLOH0BBW7RVMR1/covid-19-pneumonia-12.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585257743026-22I88WSCY8411O2NQBG2/Screen+Shot+2020-03-26+at+5.21.55+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023942491-AZ3SNMT8GQPZFCEN0O7K/Screen+Shot+2020-03-24+at+12.25.18+AM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 ここでは一塩基性開裂部位を示す「R」と多塩基性開裂部位を示す「R×R/K R」が表示されています。青色の星マーク（鶏の図の中の）は、どのような組織に感染し得るかを示します（Han et al. 2020より改変）。 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585299424299-6S5OG0FACTXYG0D17RWV/ab_best.gif COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584997212332-95BGNKYV8C3RE8PTU0TY/Screen+Shot+2020-03-23+at+4.59.45+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：後編 https://leelabvirus.host/covid19-japanese/exponential-growth monthly 0.5 2020-04-03 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104034506-15YXI2ZC4ATSZNL41JV5/Screen+Shot+2020-03-24+at+10.40.09+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104225085-PQRAV1PWXNAS0ES8ISD8/Screen+Shot+2020-03-24+at+10.43.33+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104316489-GJ318ROHPURNL1789VQN/Screen+Shot+2020-03-24+at+10.45.06+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104476304-K8EIM42R56FRD5GCIUXY/Screen%2BShot%2B2020-03-24%2Bat%2B10.46.48%2BPM.jpg COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104537244-EQ20RRFS85OR2F5N84GG/Screen+Shot+2020-03-24+at+10.48.48+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104670141-849SK7GFCILTKTH32V98/Screen+Shot+2020-03-24+at+10.50.58+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105358541-4KM6BFPRO6538OQUWRAY/Screen+Shot+2020-03-24+at+11.02.27+PM.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105600369-TBP2L7D36F1X4FY0X0Q5/F1.large.jpg COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585142850801-CYIY41BXT1JRT26CP2M9/Picture1.png COVID-19 Translated: Japanese - なぜ世界で”たった”21,000人が死んだウイルスをこんなにも心配しているのか？ - Rachel Temple 博士 Rachelはペンシルバニア州立大学でウイルス学の博士号を取得しました。その後、ダートマス大学のJoshua Obar博士の研究室で研究に従事しました。Obar 博士の研究室では、インフルエンザウイルス感染に対する免疫反応と喘息などの併存疾患がどのように重症化するかを研究しました。現在、レイチェルはフィラデルフィアの STEMCELL TECHNOLOGIES で働いています。 https://leelabvirus.host/covid19-japanese/origins-part1 monthly 0.5 2020-03-30 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584984626945-FFELXU3VT646FCG8E40C/2010-Intermediate-Horseshoe-Bat-1024x676.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584986548814-HRTGVVEMAI5YXJ0431KI/zoonotic2.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988142239-VH8LLWFDQM8AH1R6N7ZB/Viral+Mutations.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988143172-8LKM0JS52PHKRERARSGB/selection.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989033799-GFRYRUXLV9FN4NRY13FJ/sars_newsweek.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989040386-FEYZMFKRF5NQH5CBKJCJ/Screen+Shot+2020-03-23+at+2.42.38+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990027373-WTIBJ6VFCQBXS8YLM338/Malay_civet.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 Kalyan Varma氏とWikimedia Commons氏の提供。 これは2003年に発生したSARSの原型となったコウモリとヒトの中間宿主と推定されているハクビシン。Kalyan Varmaとウィキメディア・コモンズ提供。 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990717390-E3RA549S7J5JQQBVP5A3/khan_phylogenetic+tree.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 系統樹の図、提供：Khan Academy 系統樹のイラスト、Khan Academy提供 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992147215-RSMARYIUHZUHJH2TDZY0/Screen+Shot+2020-03-23+at+3.35.09+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992538565-QHLAAUB5IP35NEJ2YF3W/Genomic+Organization+of+SARS-CoV-2.jpeg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 SARS-CoV-2ゲノムを模式的に表示したものです。スパイクタンパク質の3D構造を見ることができ、ハイライト表示されているのは、受容体結合ドメイン（RBD）と呼ばれる特定の領域である。これは、ヒト表面タンパク質であるACE2に結合していることが報告されています。 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585063152777-ILCDN87BI91YRX8GGXXO/likeness_genome.jpeg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065252768-7MSQQZER470JNK591X3K/spike.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065273090-CZLEHN1VJ4P2L9EQS0H4/SpikeProtein.jpeg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023704320-NLVUOZV4J0H9F2ANAS35/pangolin.jpg COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 Firdia Lisnawati: マレーのセンザンコウの画像 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023745812-SHGOORJLDOVIC7BFPSJI/Screen+Shot+2020-03-23+at+4.05.16+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 Xiao氏らの図を引用。 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585597892637-HZ69A77J3WIZADMQ1NS9/Screen+Shot+2020-03-30+at+3.51.14+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: Japanese - SARS-CoV-2の起源：その1 https://leelabvirus.host/covid19-japanese/introduction monthly 0.5 2020-03-30 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585521146099-3N712LYMMCYJVJR9EZRZ/Screen+Shot+2020-03-29+at+6.32.16+PM.png COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585521538927-ZYJYSFVUJZ482L091EZQ/Respiratory%2BVirus%2BInfection%2BCycle.png COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522030412-8N792E5VH58VQHD9N6XF/Covid-19-Transmission-graphic-01.gif COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522175269-8K2408L258NSD2P0X1YX/Covid-19-curves-graphic-social-v3.gif COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522288093-PU3A5AZZ7RE9WEBKBXZU/Smokey-COVID-19.jpg COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522364434-SFF3CVBL2KR3CMIGT1YJ/social-distancing-infograph-eng-1.png COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522545721-Z7MQAVISRIW9NWQ5AOA1/PHOTO-2020-03-22-17-44-28.jpg COVID-19 Translated: Japanese - COVID-19を引き起こす新規コロナウイルスの解説： https://leelabvirus.host/covid19-french daily 0.75 2020-03-30 https://leelabvirus.host/covid19-french/lorigine-partie1 monthly 0.5 2020-03-30 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584984626945-FFELXU3VT646FCG8E40C/2010-Intermediate-Horseshoe-Bat-1024x676.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Image avec l'aimable autorisation de MammalWatching.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584986548814-HRTGVVEMAI5YXJ0431KI/zoonotic2.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988142239-VH8LLWFDQM8AH1R6N7ZB/Viral+Mutations.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988143172-8LKM0JS52PHKRERARSGB/selection.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989033799-GFRYRUXLV9FN4NRY13FJ/sars_newsweek.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989040386-FEYZMFKRF5NQH5CBKJCJ/Screen+Shot+2020-03-23+at+2.42.38+PM.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990027373-WTIBJ6VFCQBXS8YLM338/Malay_civet.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Il s'agit d'une civette, l'hôte intermédiaire présumé entre les chauves-souris et les humains pour l'épidémie initiale de SRAS de 2003. Avec l'aimable autorisation de Kalyan Varma et de Wikimedia Commons. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990717390-E3RA549S7J5JQQBVP5A3/khan_phylogenetic+tree.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Une illustration d'arbre phylogénétique, avec l'aimable autorisation de l'Académie Khan https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992147215-RSMARYIUHZUHJH2TDZY0/Screen+Shot+2020-03-23+at+3.35.09+PM.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992538565-QHLAAUB5IP35NEJ2YF3W/Genomic+Organization+of+SARS-CoV-2.jpeg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Une représentation visuelle du génome du SARS-CoV-2, avec l'aimable autorisation de Biorender. Nous pouvons voir la structure 3D de la protéine de spike et nous mettons en évidence une région particulière appelée domaine de liaison du récepteur (RBD). Il est montré lié à la protéine de surface humaine, ACE2. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585063152777-ILCDN87BI91YRX8GGXXO/likeness_genome.jpeg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065252768-7MSQQZER470JNK591X3K/spike.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065273090-CZLEHN1VJ4P2L9EQS0H4/SpikeProtein.jpeg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023704320-NLVUOZV4J0H9F2ANAS35/pangolin.jpg COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Firdia Lisnawati: AP Photo; image d’un pangolin malais https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023745812-SHGOORJLDOVIC7BFPSJI/Screen+Shot+2020-03-23+at+4.05.16+PM.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 Figure modifiée d’après Xiao et al. 2020 https://doi.org/10.1101/2020.02.17.951335 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585591916349-X95DBRKXA84UA3TK7VG6/spuechmaille.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: French - L’origine du SARS-CoV-2 : Partie 1 https://leelabvirus.host/covid19-spanish daily 0.75 2020-04-05 https://leelabvirus.host/covid19-spanish/exponential-growth monthly 0.5 2020-04-05 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104034506-15YXI2ZC4ATSZNL41JV5/Screen+Shot+2020-03-24+at+10.40.09+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104225085-PQRAV1PWXNAS0ES8ISD8/Screen+Shot+2020-03-24+at+10.43.33+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104316489-GJ318ROHPURNL1789VQN/Screen+Shot+2020-03-24+at+10.45.06+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104476304-K8EIM42R56FRD5GCIUXY/Screen%2BShot%2B2020-03-24%2Bat%2B10.46.48%2BPM.jpg COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104537244-EQ20RRFS85OR2F5N84GG/Screen+Shot+2020-03-24+at+10.48.48+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585104670141-849SK7GFCILTKTH32V98/Screen+Shot+2020-03-24+at+10.50.58+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105358541-4KM6BFPRO6538OQUWRAY/Screen+Shot+2020-03-24+at+11.02.27+PM.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585105600369-TBP2L7D36F1X4FY0X0Q5/F1.large.jpg COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586118999324-6UB7KDW807R8W1HBD50X/image-asset.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585142850801-CYIY41BXT1JRT26CP2M9/Picture1.png COVID-19 Translated: Spanish - ¿Por qué estamos tan preocupados por un virus que ha matado “solamente” a 21.000 personas en todo el planeta? - Rachel Temple, PhD Rachel obtuvo se doctoró en virología en Pennsylvania State University. Luego realizó un postdoctorado en el laboratorio del Dr. Joshua Obar, en Dartmouth College. Allí Rachel estudió la respuesta inmune a la infección por el virus de la gripe y cómo la presencia simultánea de otros padecimientos crónicos como el asma pueden aumentar la gravedad de la enfermedad. Actualmente Rachel trabaja con STEMCELL TECHNOLOGIES en el área de Philadelphia. https://leelabvirus.host/covid19-spanish/introduction-to-sars-cov2 monthly 0.5 2020-04-05 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584666660465-O2GUPA4RDH90B4CL8TNE/https%3A%2F%2Fwww.biorxiv.org%2Fcontent%2F10.1101%2F2020.03.02.972935v2.full COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584673141982-DHTJD5N8JDO0QM64JKRR/Respiratory+Virus+Infection+Cycle.png COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584896205948-J58T86C35UBCG95VH42J/https%3A%2F%2Fthespinoff.co.nz%2Fpolitics%2F22-03-2020%2Fsiouxsie-wiles-toby-morris-what-does-level-two-mean-and-why-does-it-matter%2F COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584897615626-ZJ1UVYTAUL5MZ8BINIFZ/https%3A%2F%2Fthespinoff.co.nz%2Fsociety%2F09-03-2020%2Fthe-three-phases-of-covid-19-and-how-we-can-make-it-manageable%2F COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584822128960-HP5N4F2GV7YNBOW6ED2G/Smokey-COVID-19.jpg COVID-19 Translated: Spanish - Introducción al SARS-CoV2: Solo tú puedes prevenir el COVID-19. No es una cita directa. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584823047493-1HK1B02QOY1UPOQZK8AS/social-distancing-infograph-eng-1.png COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1586118273636-56OW3CSDDYFI5G6ME4TW/Screen+Shot+2020-04-05+at+4.22.03+PM.png COVID-19 Translated: Spanish - Introducción al SARS-CoV2: https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584914534681-5HZW7FMKAZDY8J8FJ95K/PHOTO-2020-03-22-17-44-28.jpg COVID-19 Translated: Spanish - Introducción al SARS-CoV2: - Patricia Thibault, PhD Patricia es oriunda de Canadá y recibió su doctorado en la Universidad de Saskatchewan en 2014, donde estudió el virus de la hepatitis C (VHC). De 2014 a 2020 fue becaria postdoctoral en el laboratorio del Dr. Benhur Lee en Mount Sinai, donde estudió una amplia variedad de paramixovirus. Actualmente es asistente de investigación en el laboratorio del Dr. Michael C. Levin en el Departamento de Anatomía, Fisiología y Farmacología en la Facultad de Medicina de la Universidad de Saskatchewan. Twitter: @escape_mutant https://leelabvirus.host/covid19-spanish/origins-part2 monthly 0.5 2020-04-05 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585246559831-LDXHVLMLOH0BBW7RVMR1/covid-19-pneumonia-12.jpg COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585257743026-22I88WSCY8411O2NQBG2/Screen+Shot+2020-03-26+at+5.21.55+PM.png COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023942491-AZ3SNMT8GQPZFCEN0O7K/Screen+Shot+2020-03-24+at+12.25.18+AM.png COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 Aquí vemos "R" que indica el sitio de escote monobásico y "R X R/K R" que indica el sitio de escote polibásico. Las estrellas azules indican qué tejidos pueden estar infectados (modificado de Han et al. 2020). https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585299424299-6S5OG0FACTXYG0D17RWV/ab_best.gif COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584997212332-95BGNKYV8C3RE8PTU0TY/Screen+Shot+2020-03-23+at+4.59.45+PM.png COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: Spanish - Los orígenes de SARS-CoV-2: Parte 2 https://leelabvirus.host/covid19-spanish/origenes-primera-parte monthly 0.5 2020-03-30 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584984626945-FFELXU3VT646FCG8E40C/2010-Intermediate-Horseshoe-Bat-1024x676.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Imagen cortesía de MammalWatching.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584986548814-HRTGVVEMAI5YXJ0431KI/zoonotic2.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988142239-VH8LLWFDQM8AH1R6N7ZB/Viral+Mutations.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988143172-8LKM0JS52PHKRERARSGB/selection.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989033799-GFRYRUXLV9FN4NRY13FJ/sars_newsweek.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989040386-FEYZMFKRF5NQH5CBKJCJ/Screen+Shot+2020-03-23+at+2.42.38+PM.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990027373-WTIBJ6VFCQBXS8YLM338/Malay_civet.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Este es un gato civeta, el supuesto hospedero intermedio entre murciélagos y humanos en el brote original de SRAS de 2003. Cortesía de Kalyan Varma y Wikimedia Commons. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990717390-E3RA549S7J5JQQBVP5A3/khan_phylogenetic+tree.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Una ilustración del árbol filogenético, cortesía de Khan Academy. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992147215-RSMARYIUHZUHJH2TDZY0/Screen+Shot+2020-03-23+at+3.35.09+PM.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992538565-QHLAAUB5IP35NEJ2YF3W/Genomic+Organization+of+SARS-CoV-2.jpeg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Una representación visual del genoma del SARS-CoV-2, cortesía de Biorender. Podemos ver la estructura 3D de la proteína espiga y destacamos una región particular llamada dominio de unión al receptor (RBD). Se muestra unido a la proteína de superficie humana, ACE2. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585063152777-ILCDN87BI91YRX8GGXXO/likeness_genome.jpeg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065252768-7MSQQZER470JNK591X3K/spike.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065273090-CZLEHN1VJ4P2L9EQS0H4/SpikeProtein.jpeg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023704320-NLVUOZV4J0H9F2ANAS35/pangolin.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Firdia Lisnawati: Foto AP; imagen de un pangolín malayo https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023745812-SHGOORJLDOVIC7BFPSJI/Screen+Shot+2020-03-23+at+4.05.16+PM.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte Figura alterada de Xiao et al. 2020 https://doi.org/10.1101/2020.02.17.951335. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585579692906-A199DPI93OJWJDBMCQ0Y/lilianadavalos.jpg COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: Spanish - Los Orígenes del SARS-CoV-2: Primera Parte https://leelabvirus.host/covid19-traditional-chinese daily 0.75 2020-04-20 https://leelabvirus.host/covid19-traditional-chinese/origins-part1 monthly 0.5 2020-04-20 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584984626945-FFELXU3VT646FCG8E40C/2010-Intermediate-Horseshoe-Bat-1024x676.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 圖片來源 MammalWatching.com https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584986548814-HRTGVVEMAI5YXJ0431KI/zoonotic2.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988142239-VH8LLWFDQM8AH1R6N7ZB/Viral+Mutations.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584988143172-8LKM0JS52PHKRERARSGB/selection.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989033799-GFRYRUXLV9FN4NRY13FJ/sars_newsweek.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584989040386-FEYZMFKRF5NQH5CBKJCJ/Screen+Shot+2020-03-23+at+2.42.38+PM.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990027373-WTIBJ6VFCQBXS8YLM338/Malay_civet.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 這是果子狸- 在2003年SARS爆發時，被認為是蝙蝠與人類之間的中間宿主。 Courtesy of Kalyan Varma and Wikimedia Commons. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584990717390-E3RA549S7J5JQQBVP5A3/khan_phylogenetic+tree.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 A phylogenetic tree illustration, courtesy of Khan Academy https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992147215-RSMARYIUHZUHJH2TDZY0/Screen+Shot+2020-03-23+at+3.35.09+PM.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584992538565-QHLAAUB5IP35NEJ2YF3W/Genomic+Organization+of+SARS-CoV-2.jpeg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 圖示化地呈現 SARS-CoV2 的基因序列- 由 Biorender 提供。我們可以看到突刺蛋白質 (spike protein) 的3D結構，其中框起來強調的區域我們稱為受器結合位 (the receptor binding domain, RBD)，這個區域我們已知會與人類呼吸道的表面蛋白質ACE2 (Angiotensin converting enzyme 2) 結合。 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585063152777-ILCDN87BI91YRX8GGXXO/likeness_genome.jpeg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065252768-7MSQQZER470JNK591X3K/spike.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585065273090-CZLEHN1VJ4P2L9EQS0H4/SpikeProtein.jpeg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023704320-NLVUOZV4J0H9F2ANAS35/pangolin.jpg COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 Firdia Lisnawati: AP Photo; 圖為馬來西亞穿山甲 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585023745812-SHGOORJLDOVIC7BFPSJI/Screen+Shot+2020-03-23+at+4.05.16+PM.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 Figure altered from Xiao et al. 2020 https://doi.org/10.1101/2020.02.17.951335. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585000565112-I1H8Y0HIA9JNZSBD5Y9K/Screen+Shot+2020-03-23+at+5.55.09+PM.png COVID-19 Translated: Traditional Chinese - SARS-CoV2 的源起: Part 1 https://leelabvirus.host/covid19-traditional-chinese/asymptomatic-transmission monthly 0.5 2020-04-14 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585452316931-XGY5UDJU3KHHJR8KQOSK/Social_Distancing_Subway_Example_Gif.gif COVID-19 Translated: Traditional Chinese - 2019年冠狀病毒疾病（COVID-19）：潛伏期傳播、年齡和疾病之關連性 病毒脫落如何促進公共空間的病毒傳播：嚴格的社交距離可減少此類傳播事件發生。圖片由Griffin Haas提供 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585446065582-WWMLWKLXTIH7HJTF2PE2/Pic+GH.png COVID-19 Translated: Traditional Chinese - 2019年冠狀病毒疾病（COVID-19）：潛伏期傳播、年齡和疾病之關連性 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585522122043-QTW0E7E2U9UQRDH4UE6J/CDC_Covid19_Social_Distancing_Tweet.png COVID-19 Translated: Traditional Chinese - 2019年冠狀病毒疾病（COVID-19）：潛伏期傳播、年齡和疾病之關連性 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585525129012-UZIQ9K8CRO6DEC3OITHL/Covid-19-Transmission-graphic-01.gif COVID-19 Translated: Traditional Chinese - 2019年冠狀病毒疾病（COVID-19）：潛伏期傳播、年齡和疾病之關連性 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1585446343597-FMS4Z6W27GYG24KXD3X6/GH.png COVID-19 Translated: Traditional Chinese - 2019年冠狀病毒疾病（COVID-19）：潛伏期傳播、年齡和疾病之關連性 - 作者：Griffin Haas Griffin於杜克大學 (Duke University) 取得生物學學士學位，目前是紐約西奈山伊坎醫學院的博士班學生。2020年起，Griffin加入Dr. Benhur Lee實驗室，參與Henipavirus和宿主之蛋白質交互作用的研究。閒暇之餘，Griffin也喜歡繪製微生物學和感染症相關的科普示意圖。 Email: griffin.haas@icahn.mssm.edu Twitter: @GriffinHaas https://leelabvirus.host/covid19-traditional-chinese/introduction monthly 0.5 2020-04-10 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584666660465-O2GUPA4RDH90B4CL8TNE/https%3A%2F%2Fwww.biorxiv.org%2Fcontent%2F10.1101%2F2020.03.02.972935v2.full COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584673141982-DHTJD5N8JDO0QM64JKRR/Respiratory+Virus+Infection+Cycle.png COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584896205948-J58T86C35UBCG95VH42J/https%3A%2F%2Fthespinoff.co.nz%2Fpolitics%2F22-03-2020%2Fsiouxsie-wiles-toby-morris-what-does-level-two-mean-and-why-does-it-matter%2F COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584897615626-ZJ1UVYTAUL5MZ8BINIFZ/https%3A%2F%2Fthespinoff.co.nz%2Fsociety%2F09-03-2020%2Fthe-three-phases-of-covid-19-and-how-we-can-make-it-manageable%2F COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584822128960-HP5N4F2GV7YNBOW6ED2G/Smokey-COVID-19.jpg COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 Not a direct quote. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584823047493-1HK1B02QOY1UPOQZK8AS/social-distancing-infograph-eng-1.png COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1584914534681-5HZW7FMKAZDY8J8FJ95K/PHOTO-2020-03-22-17-44-28.jpg COVID-19 Translated: Traditional Chinese - 新型冠狀病毒 (Severe acute respiratory syndrome coronavirus 2, SARS-CoV2) 簡介 - 作者：Patricia Thibault, PhD Patricia 來自加拿大，其專注於C型肝炎病毒領域的研究且於2014年在University of Saskatchewan 獲得她的博士學位。自2014-2020年間在紐約西奈山伊坎醫學院 Dr. Benhur Lee 的實驗室擔任博士後研究員並醉心於副黏液病毒的相關研究。目前為任職於 Dr. Michael C. Levin的實驗室 (Department of Anatomy, Physiology, and Pharmacology in the College of Medicine at the University of Saskatchewan) 擔任助理研究員。 推特: @escape_mutant https://leelabvirus.host/contact-us daily 0.75 2019-08-26 https://leelabvirus.host/team daily 0.75 2026-01-13 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/c31e1a08-4b8f-4bc4-bf5d-09ea7afc1b05/Benhur_Potrait.NYC_2017.jpg Team - Benhur Lee, MD Fellow, American Academy of Microbiology Principal Investigator Professor, Department of Microbiology Ward-Coleman Chair in Microbiology Send email MD, Alpha Omega Alpha, Yale University School of Medicine, 1995 BSc (magna cum laude) Santa Clara University, 1988 My lab is my surrogate family, I’m passionate about mentoring and #SciComm. I’m insatiably curious about molecular virus-host interactions, And I’m on a life long “Quest for good explanations.” https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/e3ab59cd-6393-4c3d-a674-fab80735666e/PKD.jpg Team - Pratyush Kumar Das, PhD Senior Scientist Laboratory Manager/Lab Safety Officer pratyush.das@mssm.edu Ph.D. Gene Technology, University of Tartu, Estonia, 2015 I joined Dr. Benhur Lee’s lab as a Senior Scientist in March 2025 to study the molecular biology of paramyxoviruses with focus on virus mediated hijacking of host cell machinery. Along with doing basic molecular virology investigations, I like to learn new experimental techniques to complement my research. In my previous positions: 1) as a postdoc with Dr. Margaret Kielian at Albert Einstein College of Medicine, NY, I studied entry and exit mechanism of Rubella virus 2) as a research fellow with Dr. Jussi Taipale at University of Helsinki, Finland, I studied DNA binding specificity of human transcription factors using high throughput SELEX and next generation sequencing 3) as a Ph.D. student with Dr. Andres Merits at University of Tartu, Estonia I characterized enzymatic activities of alphavirus nonstructural proteins. You may find my publications here. Along with conducting research, as Laboratory Manager and Lab Safety Officer (LSO), in co-ordination with William and Benhur, I oversee, manage and optimize our lab operations. In my free time I enjoy playing piano, doing weight training and cooking. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/a51c839b-853d-4ecb-9fce-3f559cead8d9/William+Website+picture.jpeg Team - William Klain, MS Associate Researcher I klain.w@northeastern.edu B.S. and M.S. in Bioengineering with a Cell and Tissue Engineering Concentration from Northeastern University, 2023. It is a pleasure to say my passion for virology has lead me to conduct a great variety of intriguing experiments for the Benhur Lee Lab. I am currently a technician in the lab and have taken up some lab managerial duties as well. I am involved in research pertaining to emerging zoonotic pathogens, more specifically bat paramyxoviruses, investigating virus-host interactions. I am highly interested in viruses with epidemic potential, since there could be a real chance they could spread to humans, as NiV unfortunately already has. Exploring mechanisms of how these viruses bind, replicate, and infect at a cellular level is crucial for designing therapeutic approaches against them. I am glad I am surrounded by a lab full of wonderful people who work together for this purpose. Outside of the lab I enjoy listening/making music, playing/watching basketball & soccer(Proud Liverpool Supporter), and going to the beach for some gnarly waves. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1568224179663-QU9S6N2Z74EKX0JQBHY5/Chuan-Tien.jpg Team - Chuan Tien Hung, PhD Associate Scientist chuan-tien.hung@mssm.edu PhD Graduate Institute of Biomedical Sciences, Division of Microbiology, Chang-Gung University, Taiwan, 2016 During my PhD training, I’m always fascinated by how virus exploit cellular factors to potentiate its own propagation. Since joining the lab in 2017, my work has been primarily focused on the viral structural protein matrix, which is critical to viral assembly and budding. Our matrix interactome reveals paramyxovirus-matrix interact with wide variety of host factors and we are interested in some of these interaction.s I now try to decipher the non-structural role of matrix in host-pathogen interactions and its outcome for the virus replication. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/a9a69815-ad08-43d3-9053-771857d88eb9/Mo+image+for+website.png Team https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/cac22f5c-fc5b-4fb1-a7f4-4440c47b280e/Rebecca+lab+website+image.png Team - Rebecca Reis, PhD Post-doc Rebecca.reis@mssm.edu PhD in Microbiology from The University of Chicago, 2023 BS in Biology from Saint Mary’s College, 2016 BS in Philosophy from Saint Mary’s College, 2016 Since joining the lab in 2023, I’ve had the opportunity to expand me research into new and exciting areas of paramyxovirus biology. My interests focus primarily on understanding the innate immune evasion mechanisms of paramyxoviruses, using computational approaches to understand conserved features of paramyxovirus biology, and using paramyxoviruses as vectors. Outside of lab you can find me trying new restaurants, running, or listening to live music around the city. https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/a38dfbb4-b1cf-4646-b465-c0e98e773779/Griff+website+picture.png Team https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/39523c32-a9ad-487d-837a-50eea4b6e3c3/AGS_F.jpg https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/ae01c22d-95a9-47f3-9836-35878f269656/Picture1.png https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/c1b2f877-f7cb-499e-b80e-3d3e508e693b/image_PNG.png https://leelabvirus.host/new-page daily 0.75 2026-02-07 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567526948442-0G773FEC8A7ISJ5759QM/Screen+Shot+2019-09-04+at+12.05.19+AM.png Publications Click image to go to book https://leelabvirus.host/henipavirus daily 0.75 2019-08-26 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567525660992-LDD5HN94CUH80D6BP3EM/Screen+Shot+2019-09-03+at+11.46.41+PM.png * Henipavirus Nipah Virus Induced Syncytia in Cell Culture https://leelabvirus.host/broad-spectrum-antiviral-strategies-1 daily 0.75 2019-08-26 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567619265455-LF78N93LPEU7FZ4MGZH0/Screen+Shot+2019-09-05+at+1.44.59+AM+copy.jpg * Paramyxovirus Matrix Protein https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567618603204-QLZ6C7PMUS71H3VRL27Q/3D%2BImage_Matrix%2Bin%2BNucleus_VHS%2BCover_7-2014.jpg * Paramyxovirus Matrix Protein The Nipah virus matrix protein traffics through the nucleus during infection. 3D confocal micrograph of HeLa cells infected with Nipah virus for 12h. The viral matrix protein is shown in green, nuclei in blue, and the F-actin cytoskeleton in red. https://leelabvirus.host/emerging-infectious-diseases daily 0.75 2020-04-20 https://leelabvirus.host/about daily 0.75 2021-03-12 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/2fca0e82-82b9-48fe-ae1c-9c6213e4ba13/LeeLab+Bowling.09-07-2019.jpeg Home https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566851495501-SARW0W1XEEPHL7NYARDB/department+of+microbiology.png Home https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566920401045-XTHHMXPFFQQYTPISA7J9/Lee+Lab.Vests.10-30-2015.jpg Home https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566920291567-BCKJKRBIPIOJWNULHZN7/Lee+Lab+Group+Pic%231.JPG Home https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566920574080-WSOK891YYJ3A3K68SLER/3.+BHL+with+LinFa+Wang.JPG Home Benhur with LinFa Wang at CSIRO's BSL4 lab in Geelong Australia (right before it went hot!) https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/41f5e239-ed53-4aa6-8579-b9cbfe89b9bd/Group+at+Karaoke.jpg Home https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/34ffdede-4722-425d-82af-bcd99eb48764/UCLA+Halloween.jpg Home https://leelabvirus.host/gene-therapy daily 0.75 2019-08-26 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567622743655-ZTWY3UDPXX9KRD34CH2K/Figure+5.3.png * Next Generation Gene Editing https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567622802446-R1DX8GTU9EK2DAWIJJEG/Figure+5.4.png * Next Generation Gene Editing https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567622989404-5CZUAYVO2822SBH23PA9/Figure+5.1.png * Next Generation Gene Editing https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1567623179937-6F0A9EQKGPSZ1E7LOIBU/Figure+5.2.png * Next Generation Gene Editing https://leelabvirus.host/alumni daily 0.75 2025-04-11 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923525807-ZKEJXOHB3TPGAGYIGA59/Screen+Shot+2019-08-28+at+12.29.42+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923533571-H8W7IWV163STGHUZ2QRB/Screen+Shot+2019-08-28+at+12.29.56+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923539848-4E9LN516OIYKWPIG7NW2/Screen+Shot+2019-08-28+at+12.30.20+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923539418-K9K5GAVMFANJV51W9HPN/Screen+Shot+2019-08-28+at+12.30.58+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923756764-TFC8PRM8LSQYOSJ30CC2/Screen+Shot+2019-08-28+at+12.33.13+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923757419-VAR3S0I2HHW4PNEMPDD7/Screen+Shot+2019-08-28+at+12.33.24+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923759038-TURPMBZQSPX2J05JGF5F/Screen+Shot+2019-08-28+at+12.33.42+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923757327-P1W4ZSAFMOZIK3HTSNCH/Screen+Shot+2019-08-28+at+12.33.54+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923756011-WTNIXVWKD0BGNXRHEDC6/Screen+Shot+2019-08-28+at+12.34.17+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923758055-7NQXLK1173SK8FF31CG9/Screen+Shot+2019-08-28+at+12.34.28+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923759340-QCSH1J9KQ1BGXJLKK7XD/Screen+Shot+2019-08-28+at+12.34.50+AM.png Alumni https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1566923759595-JOSYKVN4IB8X46LCRL4I/Screen+Shot+2019-08-28+at+12.35.14+AM.png Alumni https://leelabvirus.host/home daily 1.0 2019-08-29 https://leelabvirus.host/new-page-1 daily 0.75 2019-09-19 https://leelabvirus.host/next-generation-omics daily 0.75 2019-09-18 https://images.squarespace-cdn.com/content/v1/5c5a514d65019f01a2cb2be5/1562687024353-YI2JTTGZH5NEL2JDX35X/20140301_Trade-151_0124-copy.jpg * Next Generation Omics https://images.squarespace-cdn.com/content/v1/5c5a514d65019f01a2cb2be5/1562687033752-GYBC5N9IBWBEWSB8ZXJ2/20140301_Trade-151_0124-copy.jpg * Next Generation Omics https://images.squarespace-cdn.com/content/v1/5c5a514d65019f01a2cb2be5/1562687042835-DITPZLPAZ9VB5SVD9Y3U/20140301_Trade-151_0124-copy.jpg * Next Generation Omics https://leelabvirus.host/menu-4 daily 0.75 2019-10-07 https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1570147385719-DYMYXU8TFKUD3WR3CPM1/Science+Process+%26+Philosophy.Collage.jpg Topics (Click here first) - Science Process & Philosophy Science Process & Philosophy https://images.squarespace-cdn.com/content/v1/5c5a514d65019f01a2cb2be5/1562693641570-94ME5B74CS0964A8MZOO/20140301_Trade-151_0124-copy.jpg Topics (Click here first) - Dinner Bionumbers (Coming Soon) https://images.squarespace-cdn.com/content/v1/5d641f19c70045000197e615/1570174322484-8B9AUB2BYMRO98UTX5GB/Techniques+%26+Reagents.jpg Topics (Click here first) - Lunch Techniques, Reagents & Basic Cell Biology https://images.squarespace-cdn.com/content/v1/5c5a514d65019f01a2cb2be5/1562693691277-O3FWNJAHIM8OGWLAFO18/20140301_Trade-151_0124-copy.jpg Topics (Click here first) - Drinks Work-Life Balance (Coming Soon) https://leelabvirus.host/general-5 daily 0.75 2022-11-28 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847331546-NBMOOBORXBR1I52QDOEM/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847332082-XD1KMA4EER5NVQWQZJ4O/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847330913-1F0BEVH4E8EWIS3SJYLB/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847330272-BEQUDHMNDH37S90TSA0T/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847329019-GP1Z6VXLF9U75MC4JIO0/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847328311-R7PAZDQTBOBSEOWC9YQ3/20140301_Trade-151_0124-copy.jpg General 5 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1589847327684-2C1WKZU35SCT0ZV1OJOX/20140301_Trade-151_0124-copy.jpg General 5