Lee Lab Publications

Selected Publications

2022

Ikegame S, Carmichael J, Wells H, Furler R, Acklin J, Chiu HP, Oguntuyo K, Cox R, Patel A, Kowdle S, Stevens C, Eckley M, Zhan S, Lim J, Hashiguchi T, Durigon EL, Schountz T, Epstein J, Plemper R, Daszak P, Anthony S, Lee B. (2022) Assessing the zoonotic potential of a novel bat morbillivirus. Nat Microbiol, in press.  

Haas GD, Lee B. (2022) Paramyxoviruses from bats: changes in receptor specificity and their role in host adaptation. Curr Opin Virol, 58:101292.

Wells HL, Loh E, Nava A, Solorio MR, Lee MH, Lee J, Sukor JRA, Navarrete-Macias I, Liang E, Firth C, Epstein JH, Rostal MK, Zambrana-Torrelio C, Murray K, Daszak P, Goldstein T, Mazet JAK, Lee B, Hughes T, Durigon E, Anthony SJ. (2022) Classification of new morbillivirus and jeilongvirus sequences from bats sampled in Brazil and Malaysia. Arch Virol 167:1977-1987. PMC9402765

Lam A, Kirkland OO, Anderson PF, Seetharaman N, Vujovic D, Thibault PA, Azarm KD, Lee B, Rawle RJ. (2022) Single virus assay reveals membrane determinants and mechanistic features of Sendai virus budding. Biophysical J, 121:956-965. PMC8943810

Norris MJ, Husby ML, Kiosses WB, Yun J, Rennick LJ, Heiner A, Harkins S, Pokhrel R, Schendel SL, Hastie KM, Landeras-Bueno S, Salie ZL, Lee B, Chapagain PP, Maisner A, Duprex WP, Stahelin RV, Saphire EO. (2022) Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization.  Sci Adv 8(29):eabn1440. PMC9299542

Duty JA, Kraus T, Zhou H, Zhang Y, Shaabani N, Yildiz S, Du N, Singh A, Miorin L, Li D, Stegman K, Ophir S, Cao X, Atanasoff K, Lim R, Kowdle S, Carreño JM, Rivero-Nava L, Raskin A, Moreno E, Johnson S, Rathnasinghe R, Pai CI, Kehrer T, Cabral EP, Jangra S, Healy L, Singh G, Warang P, Simon V, Sordilo ME, van Bakel H, Liu Y, Sun W, Kerwin L, Palese P, Teijaro J, Schotsaert M, Krammer F, BressonD, Garcia-sastre A, Fu Y, Lee B, Powers C, Moran T, Ji H, Tortorella D, Allen R. (2022) Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants. Med 3: 705-721. PMC9359501

2021

Klingler J, Lambert GS, Itri V, Liu S, Bandres JC, Enyindah-Asonye G, Liu X, Simon V, Gleason CR, Kleiner G, Chiu HP, Hung CT, Kowdle S, Amanat F, Lee B, Zolla-Pazner S, Upadhyay C, Hioe CE. Detection of Antibody Responses Against SARS-CoV-2 in Plasma and Saliva From Vaccinated and Infected Individuals. Front Immunol. 2021 Dec 20;12:759688. PubMed PMID: 34987505

Stevens CS, Oguntuyo KY, Lee B. Proteases and variants: context matters for SARS-CoV-2 entry assays. Curr Opin Virol. 2021 Oct;50:49-58.

Ikegame S, Siddiquey MNA, Hung CT, Brambilla L, Haas G, Chiu HP, Oguntuyo KY, Stevens CS, Kowdle S, Vilardo AE, Edelstein A, Perandones C, Kamil JP, Lee B. Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants. Nat Commun. 2021 Jul 26;12(1):4598. doi: 10.1038/s41467-021-24909-9. PubMed PMID: 34312390

Ikegame S, Hashiguchi T, Hung CT, Dobrindt K, Brennand KJ, Takeda M, Lee B. Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2026027118.

Hodcroft EB, Domman DB, Snyder DJ, Oguntuyo K, Van Diest M, Densmore KH, Schwalm KC, Femling J, Carroll JL, Scott RS, Whyte MM, Edwards MD, Hull NC, Kevil CG, Vanchiere JA, Lee B, Dinwiddie DL, Cooper VS, Kamil JP. Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677. medRxiv. 2021 Feb 14;. doi: 10.1101/2021.02.12.21251658. PubMed PMID: 33594385

Rao S, Yao Y, Soares de Brito J, Yao Q, Shen AH, Watkinson RE, Kennedy AL, Coyne S, Ren C, Zeng J, Serbin AV, Studer S, Ballotti K, Harris CE, Luk K, Stevens CS, Armant M, Pinello L, Wolfe SA, Chiarle R, Shimamura A, Lee B, Newburger PE, Bauer DE. Dissecting ELANE neutropenia pathogenicity by human HSC gene editing. Cell Stem Cell. 2021 May 6;28(5):833-845.e5. PubMed PMID: 33513358.

Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis. Nature. 2021 Mar;591(7849):293-299. PMID: 33494095.

Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MNA, Schilke RM, Woolard MD, Zhang H, Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B. Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera. mBio. 2021 Feb 16;12(1). PMID: 33593976.

Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection. Cell. 2021 Jan 7;184(1):76-91.e13. PMID: 33147444

2020

Moustaqil M, Ollivier E, Chiu HP, Van Tol S, Rudolffi-Soto P, Stevens C, Bhumkar A, Hunter DJB, Freiberg AN, Jacques D, Lee B, Sierecki E, Gambin Y. SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species. Emerg Microbes Infect. 2021 Dec;10(1):178-195. doi: 10.1080/22221751.2020.1870414. PubMed PMID: 33372854; PubMed Central PMCID: PMC7850364.

Klingler J, Weiss S, Itri V, Liu X, Oguntuyo KY, Stevens C, Ikegame S, Hung CT, Enyindah-Asonye G, Amanat F, Baine I, Arinsburg S, Bandres JC, Kojic EM, Stoever J, Jurczyszak D, Bermudez-Gonzalez M, Nádas A, Liu S, Lee B, Zolla-Pazner S, Hioe CE. Role of IgM and IgA Antibodies in the Neutralization of SARS-CoV-2. J Infect Dis. 2021 Mar 29;223(6):957-970. doi: 10.1093/infdis/jiaa784 PubMed PMID: 33367897; PubMed Central PMCID: PMC7798948.

Ikegame S, Beaty SM, Stevens C, Won T, Park A, Sachs D, Hong P, Lee B,* Thibault PA*. Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity. PLoS Pathog. 2020 Oct;16(10):e1008877. doi: 10.1371/journal.ppat.1008877. eCollection 2020 Oct. PubMed PMID: 33035269; PubMed Central PMCID: PMC7577504.

Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. PubMed PMID: 32661315; PubMed Central PMCID: PMC7529989.

2019

Avanzato VA, Oguntuyo KY, Escalera-Zamudio M, Gutierrez B, Golden M, Kosakovsky Pond SL, Pryce R, Walter TS, Seow J, Doores KJ, Pybus OG, Munster VJ, Lee B*, Bowden TA*. A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex. Proc Natl Acad Sci U S A. 2019 Nov 25;. doi: 10.1073/pnas.1912503116. [Epub ahead of print] PubMed PMID: 31767754. *Co-Corresonding authors

Rima B, Balkema-Buschmann A, Dundon WG, Duprex P, Easton A, Fouchier R, Kurath G, Lamb R, Lee B, Rota P, Wang L, Ictv Report Consortium. ICTV Virus Taxonomy Profile: Paramyxoviridae. J Gen Virol. 2019 Oct 14;. doi: 10.1099/jgv.0.001328. [Epub ahead of print] PubMed PMID: 31609197.

2018

Adelman ZN, Albritton LM, Boris-Lawrie K, Buchmeier MJ, Cannon P, Cho M, DiGiusto D, Donahue JK, Federoff HJ, Hammarskjold ML, Hardison AD, Hearing P, Lee B, Lee DA, Porteus MH, Ross LF, Ross SR, Wooley DP, Zoloth L. Protect NIH's DNA advisory committee. Science. 2018 Oct 26;362(6413):409-410. doi: 10.1126/science.aav2483. PubMed PMID: 30361364.

Manganaro L, Hong P, Hernandez MM, Argyle D, Mulder LCF, Potla U, Diaz-Griffero F, Lee B, Fernandez-Sesma A, Simon V.IL-15 regulates susceptibility of CD4+ T cells to HIV infection. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9659-E9667. doi: 10.1073/pnas.1806695115. Epub 2018 Sep 26. PubMed PMID: 30257946; PubMed Central PMCID: PMC6187195.

Escaffre O, Hill T, Ikegami T, Juelich TL, Smith JK, Zhang L, Perez DE, Atkins C, Park A, Lawrence WS, Sivasubramani SK, Peel JE, Peterson JW, Lee B, Freiberg AN. Experimental Infection of Syrian Hamsters With Aerosolized Nipah Virus. J Infect Dis. 2018 Oct 5;218(10):1602-1610. doi: 10.1093/infdis/jiy357. PubMed PMID: 29912426; PubMed Central PMCID: PMC6173575.

Lee B. Greasing the receptor. Nat Microbiol. 2018 Oct;3(10):1082-1083. doi: 10.1038/s41564-018-0251-2. PubMed PMID: 30254328.

Lee B. The quest for good explanations. PLoS Pathog. 2018 Mar;14(3):e1006818. doi: 10.1371/journal.ppat.1006818. eCollection 2018 Mar. PubMed PMID: 29518152; PubMed Central PMCID: PMC5843279.

2017

Rissanen I, Ahmed AA, Azarm K, Beaty S, Hong P, Nambulli S, Duprex WP, Lee B*, Bowden TA*. Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses. Nat Commun. 2017 Jul 12;8:16060. doi: 10.1038/ncomms16060. PubMed PMID: 28699636; PubMed Central PMCID: PMC5510225. *Co-Corresponding authors

Beaty SM, Park A, Won ST, Hong P, Lyons M, Vigant F, Freiberg AN, tenOever BR, Duprex WP, Lee B. Efficient and Robust Paramyxoviridae Reverse Genetics Systems. mSphere. 2017 Mar-Apr;2(2). doi: 10.1128/mSphere.00376-16. eCollection 2017 Mar-Apr. PubMed PMID: 28405630; PubMed Central PMCID: PMC5371697.

Beaty SM, Nachbagauer R, Hirsh A, Vigant F, Duehr J, Azarm KD, Stelfox AJ, Bowden TA, Duprex WP, Krammer F, Lee B.Cross-Reactive and Cross-Neutralizing Activity of Human Mumps Antibodies Against a Novel Mumps Virus From Bats. J Infect Dis. 2017 Jan 15;215(2):209-213. doi: 10.1093/infdis/jiw534. PubMed PMID: 27811320; PubMed Central PMCID: PMC5854012.

2016

Bharaj P, Wang YE, Dawes BE, Yun TE, Park A, Yen B, Basler CF, Freiberg AN, Lee B*, Rajsbaum R*. The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. PLoS Pathog. 2016 Sep;12(9):e1005880. doi: 10.1371/journal.ppat.1005880. eCollection 2016 Sep. PubMed PMID: 27622505; PubMed Central PMCID: PMC5021333. *Co-Corresponding authors

Park A, Hong P, Won ST, Thibault PA, Vigant F, Oguntuyo KY, Taft JD, Lee B. Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing. Mol Ther Methods Clin Dev. 2016;3:16057. doi: 10.1038/mtm.2016.57. eCollection 2016. PubMed PMID: 27606350; PubMed Central PMCID: PMC4996130.

Park A, Yun T, Vigant F, Pernet O, Won ST, Dawes BE, Bartkowski W, Freiberg AN, Lee B. Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway. PLoS Pathog. 2016 May;12(5):e1005659. doi: 10.1371/journal.ppat.1005659. eCollection 2016 May. PubMed PMID: 27203423; PubMed Central PMCID: PMC4874542.

Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, Mansouri D, Francois-Newton V, Daussy CF, Rodriguez MR, Lenschow DJ, Freiberg AN, Tortorella D, Piehler J, Lee B, García-Sastre A, Pellegrini S, Bogunovic D. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016 May 19;7:11496. doi: 10.1038/ncomms11496. PubMed PMID: 27193971; PubMed Central PMCID: PMC4873964.

Zeltina A, Bowden TA, Lee B. Emerging Paramyxoviruses: Receptor Tropism and Zoonotic Potential. PLoS Pathog. 2016 Feb;12(2):e1005390. doi: 10.1371/journal.ppat.1005390. eCollection 2016 Feb. PubMed PMID: 26915013; PubMed Central PMCID: PMC4767434.

Borisevich V, Lee B, Hickey A, DeBuysscher B, Broder CC, Feldmann H, Rockx B. Escape From Monoclonal Antibody Neutralization Affects Henipavirus Fitness In Vitro and In Vivo. J Infect Dis. 2016 Feb 1;213(3):448-55. doi: 10.1093/infdis/jiv449. Epub 2015 Sep 10. PubMed PMID: 26357909; PubMed Central PMCID: PMC4704671.

2015

Webb NE, Montefiori DC, Lee B. Dose-response curve slope helps predict therapeutic potency and breadth of HIV broadly neutralizing antibodies. Nat Commun. 2015 Sep 29;6:8443. doi: 10.1038/ncomms9443. PubMed PMID: 26416571; PubMed Central PMCID: PMC4588098.

Vigant F, Santos NC, Lee B. Broad-spectrum antivirals against viral fusion. Nat Rev Microbiol. 2015 Jul;13(7):426-37. doi: 10.1038/nrmicro3475. Epub 2015 Jun 15. Review. PubMed PMID: 26075364; PubMed Central PMCID: PMC4554337.

Lee B*, Pernet O, Ahmed AA, Zeltina A, Beaty SM, Bowden TA*. Molecular recognition of human ephrinB2 cell surface receptor by an emergent African henipavirus. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2156-65. doi: 10.1073/pnas.1501690112. Epub 2015 Mar 30. PubMed PMID: 25825759; PubMed Central PMCID: PMC4418902. *Co-Corresponding authors

Pentecost M, Vashisht AA, Lester T, Voros T, Beaty SM, Park A, Wang YE, Yun TE, Freiberg AN, Wohlschlegel JA, Lee B. Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathog. 2015 Mar;11(3):e1004739. doi: 10.1371/journal.ppat.1004739. eCollection 2015 Mar. PubMed PMID: 25782006; PubMed Central PMCID: PMC4363627.

Yun T, Park A, Hill TE, Pernet O, Beaty SM, Juelich TL, Smith JK, Zhang L, Wang YE, Vigant F, Gao J, Wu P, Lee B*, Freiberg AN.* Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection. J Virol. 2015 Jan 15;89(2):1242-53. doi: 10.1128/JVI.02583-14. Epub 2014 Nov 12. PubMed PMID: 25392218; PubMed Central PMCID: PMC4300668. *Co-Corresponding authors

2014

Pernet O, Schneider BS, Beaty SM, LeBreton M, Yun TE, Park A, Zachariah TT, Bowden TA, Hitchens P, Ramirez CM, Daszak P, Mazet J, Freiberg AN, Wolfe ND, Lee B. Evidence for henipavirus spillover into human populations in Africa. Nat Commun. 2014 Nov 18;5:5342. doi: 10.1038/ncomms6342. PubMed PMID: 25405640; PubMed Central PMCID: PMC4237230.

Chikere K, Webb NE, Chou T, Borm K, Sterjovski J, Gorry PR, Lee B. Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies. Retrovirology. 2014 Jun 23;11:48. doi: 10.1186/1742-4690-11-48. PubMed PMID: 24957778; PubMed Central PMCID: PMC4230403.

Park A, Won ST, Pentecost M, Bartkowski W, Lee B. CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function. PLoS One. 2014;9(4):e95101. doi: 10.1371/journal.pone.0095101. eCollection 2014. PubMed PMID: 24743236; PubMed Central PMCID: PMC3990584.

2013

Lee B. HIV provides ample PAMPs for innate immune sensing. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19183-4. doi: 10.1073/pnas.1319118110. Epub 2013 Nov 13. PubMed PMID: 24225850; PubMed Central PMCID: PMC3845105.

Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B. A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog. 2013;9(4):e1003297. doi: 10.1371/journal.ppat.1003297. Epub 2013 Apr 18. PubMed PMID: 23637597; PubMed Central PMCID: PMC3630091.

Tanner LB, Lee B. The greasy response to virus infections. Cell Host Microbe. 2013 Apr 17;13(4):375-7. doi: 10.1016/j.chom.2013.04.002. PubMed PMID: 23601099; PubMed Central PMCID: PMC3654690.

Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. J Virol. 2013 Feb;87(4):2094-108. doi: 10.1128/JVI.02032-12. Epub 2012 Nov 28. PubMed PMID: 23192877; PubMed Central PMCID: PMC3571488.

Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity. 2013 Jan 24;38(1):92-105. doi: 10.1016/j.immuni.2012.11.005. Epub 2012 Dec 27. PubMed PMID: 23273844; PubMed Central PMCID: PMC3698975.

Chikere K, Chou T, Gorry PR, Lee B. Affinofile profiling: how efficiency of CD4/CCR5 usage impacts the biological and pathogenic phenotype of HIV. Virology. 2013 Jan 5;435(1):81-91. doi: 10.1016/j.virol.2012.09.043. Review. PubMed PMID: 23217618; PubMed Central PMCID: PMC3522187.

2012

Biering SB, Huang A, Vu AT, Robinson LR, Bradel-Tretheway B, Choi E, Lee B, Aguilar HC. N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralization. J Virol. 2012 Nov;86(22):11991-2002. doi: 10.1128/JVI.01304-12. Epub 2012 Aug 22. PubMed PMID: 22915812; PubMed Central PMCID: PMC3486489.

Maar D, Harmon B, Chu D, Schulz B, Aguilar HC, Lee B, Negrete OA. Cysteines in the stalk of the nipah virus G glycoprotein are located in a distinct subdomain critical for fusion activation. J Virol. 2012 Jun;86(12):6632-42. doi: 10.1128/JVI.00076-12. Epub 2012 Apr 11. PubMed PMID: 22496210; PubMed Central PMCID: PMC3393546.

Wang YE, Pernet O, Lee B. Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers. Biol Cell. 2012 Mar;104(3):121-38. doi: 10.1111/boc.201100105. Epub 2011 Dec 28. Review. PubMed PMID: 22188262; PubMed Central PMCID: PMC3625690.

Lee B, Rota PA. Current Topics in Microbiology and Immunology. Berlin: Springer; 2012. 237p.

2011

Lee B. Containing the contagion: treating the virus that inspired the film. Sci Transl Med. 2011 Oct 19;3(105):105fs6. doi: 10.1126/scitranslmed.3003245. PubMed PMID: 22013121; PubMed Central PMCID: PMC3345275.

Lee B, Ataman ZA. Modes of paramyxovirus fusion: a Henipavirus perspective. Trends Microbiol. 2011 Aug;19(8):389-99. doi: 10.1016/j.tim.2011.03.005. Epub 2011 Apr 20. Review. PubMed PMID: 21511478; PubMed Central PMCID: PMC3264399.

Bi S, Hong PW, Lee B, Baum LG. Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10650-5. doi: 10.1073/pnas.1017954108. Epub 2011 Jun 13. PubMed PMID: 21670307; PubMed Central PMCID: PMC3127870.

Mirza AM, Aguilar HC, Zhu Q, Mahon PJ, Rota PA, Lee B, Iorio RM. Triggering of the newcastle disease virus fusion protein by a chimeric attachment protein that binds to Nipah virus receptors. J Biol Chem. 2011 May 20;286(20):17851-60. doi: 10.1074/jbc.M111.233965. Epub 2011 Apr 1. PubMed PMID: 21460213; PubMed Central PMCID: PMC3093860.

2010

Wang YE, Park A, Lake M, Pentecost M, Torres B, Yun TE, Wolf MC, Holbrook MR, Freiberg AN, Lee B. Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding. PLoS Pathog. 2010 Nov 11;6(11):e1001186. doi: 10.1371/journal.ppat.1001186. PubMed PMID: 21085610; PubMed Central PMCID: PMC2978725.

Aguilar HC, Aspericueta V, Robinson LR, Aanensen KE, Lee B. A quantitative and kinetic fusion protein-triggering assay can discern distinct steps in the nipah virus membrane fusion cascade. J Virol. 2010 Aug;84(16):8033-41. doi: 10.1128/JVI.00469-10. Epub 2010 Jun 2. PubMed PMID: 20519383; PubMed Central PMCID: PMC2916531.

Garner OB, Aguilar HC, Fulcher JA, Levroney EL, Harrison R, Wright L, Robinson LR, Aspericueta V, Panico M, Haslam SM, Morris HR, Dell A, Lee B, Baum LG. Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation. PLoS Pathog. 2010 Jul 15;6(7):e1000993. doi: 10.1371/journal.ppat.1000993. PubMed PMID: 20657665; PubMed Central PMCID: PMC2904771.

Shimizu S, Hong P, Arumugam B, Pokomo L, Boyer J, Koizumi N, Kittipongdaja P, Chen A, Bristol G, Galic Z, Zack JA, Yang O, Chen IS, Lee B, An DS. A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood. 2010 Feb 25;115(8):1534-44. doi: 10.1182/blood-2009-04-215855. Epub 2009 Dec 17. PubMed PMID: 20018916; PubMed Central PMCID: PMC2830759.

Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. PubMed PMID: 20133606; PubMed Central PMCID: PMC2840368.

2009

Liang M, Morizono K, Pariente N, Kamata M, Lee B, Chen IS. Targeted transduction via CD4 by a lentiviral vector uses a clathrin-mediated entry pathway. J Virol. 2009 Dec;83(24):13026-31. doi: 10.1128/JVI.01530-09. Epub 2009 Sep 30. PubMed PMID: 19793825; PubMed Central PMCID: PMC2786851.

Agrawal-Gamse C, Lee FH, Haggarty B, Jordan AP, Yi Y, Lee B, Collman RG, Hoxie JA, Doms RW, Laakso MM. Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4. J Virol. 2009 Nov;83(21):11005-15. doi: 10.1128/JVI.01238-09. Epub 2009 Aug 19. PubMed PMID: 19692476; PubMed Central PMCID: PMC2772790.

Johnston SH, Lobritz MA, Nguyen S, Lassen K, Delair S, Posta F, Bryson YJ, Arts EJ, Chou T, Lee B. A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. J Virol. 2009 Nov;83(21):11016-26. doi: 10.1128/JVI.01242-09. Epub 2009 Aug 19. PubMed PMID: 19692480; PubMed Central PMCID: PMC2772777.

Fulcher JA, Chang MH, Wang S, Almazan T, Hashimi ST, Eriksson AU, Wen X, Pang M, Baum LG, Singh RR, Lee B. Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling. J Biol Chem. 2009 Sep 25;284(39):26860-70. doi: 10.1074/jbc.M109.037507. Epub 2009 Jul 27. PubMed PMID: 19635795; PubMed Central PMCID: PMC2785374.

Hashimi ST, Fulcher JA, Chang MH, Gov L, Wang S, Lee B. MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood. 2009 Jul 9;114(2):404-14. doi: 10.1182/blood-2008-09-179150. Epub 2009 Apr 27. PubMed PMID: 19398721; PubMed Central PMCID: PMC2927176.

Aguilar HC, Ataman ZA, Aspericueta V, Fang AQ, Stroud M, Negrete OA, Kammerer RA, Lee B. A novel receptor-induced activation site in the Nipah virus attachment glycoprotein (G) involved in triggering the fusion glycoprotein (F). J Biol Chem. 2009 Jan 16;284(3):1628-35. doi: 10.1074/jbc.M807469200. Epub 2008 Nov 19. PubMed PMID: 19019819; PubMed Central PMCID: PMC2615506.

2008 and earlier

Lee B, Ataman ZA, Jin L. Evil versus 'eph-ective' use of ephrin-B2. Nat Struct Mol Biol. 2008 Jun;15(6):540-2. doi: 10.1038/nsmb0608-540. PubMed PMID: 18523462.

Negrete OA, Chu D, Aguilar HC, Lee B. Single amino acid changes in the Nipah and Hendra virus attachment glycoproteins distinguish ephrinB2 from ephrinB3 usage. J Virol. 2007 Oct;81(19):10804-14. doi: 10.1128/JVI.00999-07. Epub 2007 Jul 25. PubMed PMID: 17652392; PubMed Central PMCID: PMC2045465.

Nassanian H, Sanchez AM, Lo A, Bradley KA, Lee B. Efficient construction of an inverted minimal H1 promoter driven siRNA expression cassette: facilitation of promoter and siRNA sequence exchange. PLoS One. 2007 Aug 22;2(8):e767. doi: 10.1371/journal.pone.0000767. PubMed PMID: 17712415; PubMed Central PMCID: PMC1942083.

Hong PW, Nguyen S, Young S, Su SV, Lee B. Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120. J Virol. 2007 Aug;81(15):8325-36. doi: 10.1128/JVI.01765-06. Epub 2007 May 23. PubMed PMID: 17522223; PubMed Central PMCID: PMC1951277.

Aguilar HC, Matreyek KA, Choi DY, Filone CM, Young S, Lee B. Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signaling. J Virol. 2007 May;81(9):4520-32. doi: 10.1128/JVI.02205-06. Epub 2007 Feb 14. PubMed PMID: 17301148; PubMed Central PMCID: PMC1900187.

Wolf MC, Negrete OA, Lee B. Pathobiology of henipavirus entry: insights into therapeutic strategies. Future Virology. 2007 May; 2(3):267-82. doi: 10.2217/17460794.2.3.267.

Lee B. Envelope-receptor interactions in Nipah virus pathobiology. Ann N Y Acad Sci. 2007 Apr;1102:51-65. doi: 10.1196/annals.1408.004. Review. PubMed PMID: 17470911.

Schowalter RM, Wurth MA, Aguilar HC, Lee B, Moncman CL, McCann RO, Dutch RE. Rho GTPase activity modulates paramyxovirus fusion protein-mediated cell-cell fusion. Virology. 2006 Jul 5;350(2):323-34. doi: 10.1016/j.virol.2006.01.033. Epub 2006 Feb 28. PubMed PMID: 16500690.

Maldonado-Arocho FJ, Fulcher JA, Lee B, Bradley KA. Anthrax oedema toxin induces anthrax toxin receptor expression in monocyte-derived cells. Mol Microbiol. 2006 Jul;61(2):324-37. doi: 10.1111/j.1365-2958.2006.05232.x. PubMed PMID: 16856939.

Fulcher JA, Hashimi ST, Levroney EL, Pang M, Gurney KB, Baum LG, Lee B. Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix. J Immunol. 2006 Jul 1;177(1):216-26. doi: 10.4049/jimmunol.177.1.216. PubMed PMID: 16785517.

Aguilar HC, Matreyek KA, Filone CM, Hashimi ST, Levroney EL, Negrete OA, Bertolotti-Ciarlet A, Choi DY, McHardy I, Fulcher JA, Su SV, Wolf MC, Kohatsu L, Baum LG, Lee B. N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry. J Virol. 2006 May;80(10):4878-89. doi: 10.1128/JVI.80.10.4878-4889.2006. PubMed PMID: 16641279; PubMed Central PMCID: PMC1472062.

Negrete OA, Wolf MC, Aguilar HC, Enterlein S, Wang W, Mühlberger E, Su SV, Bertolotti-Ciarlet A, Flick R, Lee B. Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus. PLoS Pathog. 2006 Feb;2(2):e7. doi: 10.1371/journal.ppat.0020007. Epub 2006 Feb 10. PubMed PMID: 16477309; PubMed Central PMCID: PMC1361355.

Negrete OA, Levroney EL, Aguilar HC, Bertolotti-Ciarlet A, Nazarian R, Tajyar S, Lee B. EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus. Nature. 2005 Jul 21;436(7049):401-5. doi: 10.1038/nature03838. Epub 2005 Jul 6. PubMed PMID: 16007075.

Levroney EL, Aguilar HC, Fulcher JA, Kohatsu L, Pace KE, Pang M, Gurney KB, Baum LG, Lee B. Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines. J Immunol. 2005 Jul 1;175(1):413-20. doi: 10.4049/jimmunol.175.1.413. PubMed PMID: 15972675; PubMed Central PMCID: PMC4428613.

Gurney KB, Elliott J, Nassanian H, Song C, Soilleux E, McGowan I, Anton PA, Lee B. Binding and transfer of human immunodeficiency virus by DC-SIGN+ cells in human rectal mucosa. J Virol. 2005 May;79(9):5762-73. doi: 10.1128/JVI.79.9.5762-5773.2005. PubMed PMID: 15827191; PubMed Central PMCID: PMC1082722.

Morizono K, Xie Y, Ringpis GE, Johnson M, Nassanian H, Lee B, Wu L, Chen IS. Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection. Nat Med. 2005 Mar;11(3):346-52. doi: 10.1038/nm1192. Epub 2005 Feb 13. PubMed PMID: 15711560.

Su SV, Hong P, Baik S, Negrete OA, Gurney KB, Lee B. DC-SIGN binds to HIV-1 glycoprotein 120 in a distinct but overlapping fashion compared with ICAM-2 and ICAM-3. J Biol Chem. 2004 Apr 30;279(18):19122-32. doi: 10.1074/jbc.M400184200. Epub 2004 Feb 16. PubMed PMID: 14970226.

de Parseval A, Su SV, Elder JH, Lee B. Specific interaction of feline immunodeficiency virus surface glycoprotein with human DC-SIGN. J Virol. 2004 Mar;78(5):2597-600. doi: 10.1128/jvi.78.5.2597-2600.2004. PubMed PMID: 14963164; PubMed Central PMCID: PMC369267.

Su SV, Gurney KB, Lee B. Sugar and spice: viral envelope-DC-SIGN interactions in HIV pathogenesis. Curr HIV Res. 2003 Jan;1(1):87-99. Review. PubMed PMID: 15043214.

Hong PW, Flummerfelt KB, de Parseval A, Gurney K, Elder JH, Lee B. Human immunodeficiency virus envelope (gp120) binding to DC-SIGN and primary dendritic cells is carbohydrate dependent but does not involve 2G12 or cyanovirin binding sites: implications for structural analyses of gp120-DC-SIGN binding. J Virol. 2002 Dec;76(24):12855-65. doi: 10.1128/jvi.76.24.12855-12865.2002. PubMed PMID: 12438611; PubMed Central PMCID: PMC136699.

Soilleux EJ, Morris LS, Rushbrook S, Lee B, Coleman N. Expression of human immunodeficiency virus (HIV)-binding lectin DC-SIGNR: Consequences for HIV infection and immunity. Hum Pathol. 2002 Jun;33(6):652-9. doi: 10.1053/hupa.2002.124036. PubMed PMID: 12152166.

Soilleux EJ, Morris LS, Leslie G, Chehimi J, Luo Q, Levroney E, Trowsdale J, Montaner LJ, Doms RW, Weissman D, Coleman N, Lee B. Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J Leukoc Biol. 2002 Mar;71(3):445-57. PubMed PMID: 11867682.

Lee B, Doms RW. Quantification of HIV/SIV coreceptor expression . In: Cellular Aspects of HIV Infection. Cossarizza A, Kaplan DR, editors. New York, New York: John Wiley and Sons, Inc.; 2002.

Soilleux EJ, Morris LS, Lee B, Pöhlmann S, Trowsdale J, Doms RW, Coleman N. Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV. J Pathol. 2001 Dec;195(5):586-92. doi: 10.1002/path.1026. PubMed PMID: 11745695.

Lee B, Leslie G, Soilleux E, O'Doherty U, Baik S, Levroney E, Flummerfelt K, Swiggard W, Coleman N, Malim M, Doms RW.cis Expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor. J Virol. 2001 Dec;75(24):12028-38. doi: 10.1128/JVI.75.24.12028-12038.2001. PubMed PMID: 11711593; PubMed Central PMCID: PMC116098.

Lin G, Lee B, Haggarty BS, Doms RW, Hoxie JA. CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain. J Virol. 2001 Nov;75(22):10766-78. doi: 10.1128/JVI.75.22.10766-10778.2001. PubMed PMID: 11602718; PubMed Central PMCID: PMC114658.

Moonis M, Lee B, Bailer RT, Luo Q, Montaner LJ. CCR5 and CXCR4 expression correlated with X4 and R5 HIV-1 infection yet not sustained replication in Th1 and Th2 cells. AIDS. 2001 Oct 19;15(15):1941-9. doi: 10.1097/00002030-200110190-00005. PubMed PMID: 11600821.

Blanpain C, Wittamer V, Vanderwinden JM, Boom A, Renneboog B, Lee B, Le Poul E, El Asmar L, Govaerts C, Vassart G, Doms RW, Parmentier M. Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways. J Biol Chem. 2001 Jun 29;276(26):23795-804. doi: 10.1074/jbc.M100583200. Epub 2001 Apr 25. PubMed PMID: 11323418.

Pöhlmann S, Baribaud F, Lee B, Leslie GJ, Sanchez MD, Hiebenthal-Millow K, Münch J, Kirchhoff F, Doms RW. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. J Virol. 2001 May;75(10):4664-72. doi: 10.1128/JVI.75.10.4664-4672.2001. PubMed PMID: 11312337; PubMed Central PMCID: PMC114220.

Pöhlmann S, Soilleux EJ, Baribaud F, Leslie GJ, Morris LS, Trowsdale J, Lee B, Coleman N, Doms RW. DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2670-5. doi: 10.1073/pnas.051631398. PubMed PMID: 11226297; PubMed Central PMCID: PMC30196.

Puffer BA, Sharron M, Coughlan CM, Baribaud F, McManus CM, Lee B, David J, Price K, Horuk R, Tsang M, Doms RW.Expression and coreceptor function of APJ for primate immunodeficiency viruses. Virology. 2000 Oct 25;276(2):435-44. doi: 10.1006/viro.2000.0557. PubMed PMID: 11040134.

Blanpain C, Lee B, Tackoen M, Puffer B, Boom A, Libert F, Sharron M, Wittamer V, Vassart G, Doms RW, Parmentier M.Multiple nonfunctional alleles of CCR5 are frequent in various human populations. Blood. 2000 Sep 1;96(5):1638-45. PubMed PMID: 10961858.

Sharron M, Pöhlmann S, Price K, Lolis E, Tsang M, Kirchhoff F, Doms RW, Lee B. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood. 2000 Jul 1;96(1):41-9. PubMed PMID: 10891428.

Pöhlmann S, Lee B, Meister S, Krumbiegel M, Leslie G, Doms RW, Kirchhoff F. Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry. J Virol. 2000 Jun;74(11):5075-82. doi: 10.1128/jvi.74.11.5075-5082.2000. PubMed PMID: 10799581; PubMed Central PMCID: PMC110859.

Bailer RT, Lee B, Montaner LJ. IL-13 and TNF-alpha inhibit dual-tropic HIV-1 in primary macrophages by reduction of surface expression of CD4, chemokine receptors CCR5, CXCR4 and post-entry viral gene expression. Eur J Immunol. 2000 May;30(5):1340-9. doi: 10.1002/(SICI)1521-4141(200005)30:5<1340::AID-IMMU1340>3.0.CO;2-L. PubMed PMID: 10820380.

Majka M, Ratajczak J, Lee B, Honczarenko M, Douglas R, Kowalska MA, Silberstein L, Gewirtz AM, Ratajczak MZ. The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro. Stem Cells. 2000;18(2):128-38. doi: 10.1634/stemcells.18-2-128. PubMed PMID: 10742385.

Majka M, Rozmyslowicz T, Lee B, Murphy SL, Pietrzkowski Z, Gaulton GN, Silberstein L, Ratajczak MZ. Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. J Clin Invest. 1999 Dec;104(12):1739-49. doi: 10.1172/JCI7779. PubMed PMID: 10606628; PubMed Central PMCID: PMC409882.

Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood. 1999 Nov 1;94(9):2990-8. PubMed PMID: 10556181.

Wang Z, Lee B, Murray JL, Bonneau F, Sun Y, Schweickart V, Zhang T, Peiper SC. CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains. J Biol Chem. 1999 Oct 1;274(40):28413-9. doi: 10.1074/jbc.274.40.28413. PubMed PMID: 10497202.

Blanpain C, Migeotte I, Lee B, Vakili J, Doranz BJ, Govaerts C, Vassart G, Doms RW, Parmentier M. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 1999 Sep 15;94(6):1899-905. PubMed PMID: 10477718.

Blanpain C, Lee B, Vakili J, Doranz BJ, Govaerts C, Migeotte I, Sharron M, Dupriez V, Vassart G, Doms RW, Parmentier M.Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity. J Biol Chem. 1999 Jul 2;274(27):18902-8. doi: 10.1074/jbc.274.27.18902. PubMed PMID: 10383387.

Lee B, Montaner LJ. Chemokine immunobiology in HIV-1 pathogenesis. J Leukoc Biol. 1999 May;65(5):552-65. doi: 10.1002/jlb.65.5.552. Review. PubMed PMID: 10331482.

Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5215-20. doi: 10.1073/pnas.96.9.5215. PubMed PMID: 10220446; PubMed Central PMCID: PMC21844.

Lee B, Sharron M, Blanpain C, Doranz BJ, Vakili J, Setoh P, Berg E, Liu G, Guy HR, Durell SR, Parmentier M, Chang CN, Price K, Tsang M, Doms RW. Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem. 1999 Apr 2;274(14):9617-26. doi: 10.1074/jbc.274.14.9617. PubMed PMID: 10092648.

Zhang Q, Lee B, Korecka M, Li G, Weyland C, Eck S, Gessain A, Arima N, Lessin SR, Shaw LM, Luger S, Kamoun M, Wasik MA. Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia. Leuk Res.1999 Apr;23(4):373-84. doi: 10.1016/s0145-2126(98)00173-8. PubMed PMID: 10229324.

Lee B, Ratajczak J, Doms RW, Gewirtz AM, Ratajczak MZ. Coreceptor/chemokine receptor expression on human hematopoietic cells: biological implications for human immunodeficiency virus-type 1 infection. Blood. 1999 Feb 15;93(4):1145-56. PubMed PMID: 9949156.

Hariharan D, Douglas SD, Lee B, Lai JP, Campbell DE, Ho WZ. Interferon-gamma upregulates CCR5 expression in cord and adult blood mononuclear phagocytes. Blood. 1999 Feb 15;93(4):1137-44. PubMed PMID: 9949155.

Chan EF, Dowdy YG, Lee B, McKenna WG, Fox KR, Levy RJ, Wasik MA, Rook AH. A novel chemotherapeutic regimen (interferon alfa, zidovudine, and etretinate) for adult T-cell lymphoma resulting in rapid tumor destruction. J Am Acad Dermatol. 1999 Jan;40(1):116-21. doi: 10.1016/s0190-9622(99)70543-8. PubMed PMID: 9922028.

Albright AV, Shieh JT, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW, González-Scarano F. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. J Virol. 1999 Jan;73(1):205-13. PubMed PMID: 9847323; PubMed Central PMCID: PMC103824.

Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, Lee B, Doms RW, Margolick J, Buchbinder S, Goedert JJ, O'Brien TR, Hilgartner MW, Vlahov D, O'Brien SJ, Carrington M. Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science. 1998 Dec 4;282(5395):1907-11. doi: 10.1126/science.282.5395.1907. PubMed PMID: 9836644.

Edinger AL, Hoffman TL, Sharron M, Lee B, Yi Y, Choe W, Kolson DL, Mitrovic B, Zhou Y, Faulds D, Collman RG, Hesselgesser J, Horuk R, Doms RW. An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus. J Virol. 1998 Oct;72(10):7934-40. PubMed PMID: 9733831; PubMed Central PMCID: PMC110125.

Edinger AL, Hoffman TL, Sharron M, Lee B, O'Dowd B, Doms RW. Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins. Virology. 1998 Sep 30;249(2):367-78. doi: 10.1006/viro.1998.9306. PubMed PMID: 9791028.

Lee B, Doranz BJ, Rana S, Yi Y, Mellado M, Frade JM, Martinez-A C, O'Brien SJ, Dean M, Collman RG, Doms RW. Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4. J Virol. 1998 Sep;72(9):7450-8. PubMed PMID: 9696841; PubMed Central PMCID: PMC109977.

Lee B, Rucker J, Doms RW, Tsang M, Hu X, Dietz M, Bailer R, Gerard C, Sullivan N, Sodroksi J, Stantchev TS, Broder CC. β-Chemokine MDC and HIV-1 Infection. Science. 1998 July; 281(5376):487. doi: 10.1126/science.281.5376.487a.

Lee B, Doranz BJ, Ratajczak MZ, Doms RW. An intricate Web: chemokine receptors, HIV-1 and hematopoiesis. Stem Cells.1998;16(2):79-88. doi: 10.1002/stem.160079. Review. PubMed PMID: 9554031.

Lee B, Montaner LJ. Immune modulators in HIV-1 Disease . In: Human Immunodeficiency Virus: Biology, Immunology and Molecular Biology. Saksena NK, editor. Genova, Italy: Medical Systems S.P.A.; 1998.

Edinger AL, Mankowski JL, Doranz BJ, Margulies BJ, Lee B, Rucker J, Sharron M, Hoffman TL, Berson JF, Zink MC, Hirsch VM, Clements JE, Doms RW. CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14742-7. doi: 10.1073/pnas.94.26.14742. PubMed PMID: 9405683; PubMed Central PMCID: PMC25107.

Rucker J, Edinger AL, Sharron M, Samson M, Lee B, Berson JF, Yi Y, Margulies B, Collman RG, Doranz BJ, Parmentier M, Doms RW. Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses. J Virol. 1997 Dec;71(12):8999-9007. PubMed PMID: 9371556; PubMed Central PMCID: PMC230200.

Lee B, Matera AG, Ward DC, Craft J. Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis. Proc Natl Acad Sci U S A.1996 Oct 15;93(21):11471-6. doi: 10.1073/pnas.93.21.11471. PubMed PMID: 8876159; PubMed Central PMCID: PMC38081.

Lee B, Craft JE. Molecular structure and function of autoantigens in systemic sclerosis. Int Rev Immunol. 1995;12(2-4):129-44. Review. PubMed PMID: 7650417.

Selected Reviews and Book Chapters

Gómez Román R, Wang LF, Lee B, Halpin K, de Wit E, Broder CC, Rahman M, Kristiansen P, Saville M (2020) Nipah@20: Lessons learned from another virus with pandemic potential. mSphere, 2020 Jul 8;5(4):e00602-20. PMID: 32641430 

Lee B, Broder CC, Wang LF (2020) Chapter 13: Henipaviruses in Fields Virology 7th Edition, Vol. 1, DM Knipe,PM Howley, SP Whelan (Eds). Wolters Kluwer | Lippincott Williams & Wilkins. Philadelphia, PA.

Azarm KD, Lee B (2020) Differential features of fusion activation within the Paramyxoviridae. Viruses 2020 Jan 30; 12(2):161. doi: 10.3390/v12020161. PMID: 32019182 

Park A, Radoshitzky SH, Kuhn, JH, Lee B. (2018) Chapter 22: Henipaviruses in Medical Aspects of BiologicalWarfare 3rd Editon, Textbooks of Military Medicine (TMM) series, J Buzue, CK Cote, PJ Glass (Eds). Office of the Surgeon General | Borden Institute, US Army Medical Department Center and School Health Readiness Centerof Excellence. Fort Sam,. Houston, TX. 

Thibault PA, Watkinson RE, Moreira-Soto A, Drexler JF, Lee B (2017) Zoonotic potential of emergingparamyxoviruses: knowns and unknowns. Adv Virus Res, 98, 1-55. PMC5894875

Beaty SM and Lee B (2016) Constraints on the genetic and antigenic variability of measles virus. Viruses, 8, 109;doi:10.3390/v8040109. PMC4848608

Watkinson RE, Lee B (2016) Nipah virus matrix protein: Expert hacker of cellular machines. FEBS Lett, 590(15):2494-511. PMC5503110

Vigant F, Santos NC and Lee B. (2015) Broad Spectrum Antivirals against Virus Fusion. Nature Reviews Microbiology, 13(7):426-37 PMC4554337

K Chikere, Chou T, Gorry PR and Lee B. (2013) Beyond Coreceptor Usage: How the Efficiency of CD4/CCR5 usageimpacts the biological and pathogenic phenotype of HIV. Virology, 435:81-91. PMC3522187

Pernet O, Wang YE, Lee B. (2012) Henipavirus receptor usage and tropism. Current Topics in Microbiology andImmunology, 359:59-78 PMC3587688

Lee, B. and Akyol Ataman, Z. (2011) “Modes of paramyxovirus fusion: a Henipavirus perspective” Trends in Microbiology, 19:389-399 (Epub 2011 Apr 19) PMC3264399

Invited Commentaries and Perspectives or Letters to Editors

1. Lee B, Ataman ZA, and Jin L (2008) News & Views, “Evil versus ‘Eph-ective’ use of ephrin-B2” Nature Structural & Molecular Biology, 15:540-543.

2. Vigant F, Jung ME, and Lee B. (2010) Commentary, “Positive Reinforcement for Viruses” Chemistry and Biology, 17:1049-51.  PMC2998992

3. Lee B. (2011) Focus article, “Containing the Contagion: Treating the Virus that Inspired the Film” Science Translational Medicine, 3:105fs6. PMC3345275

4. Tanner LB, Lee B. (2013) Preview, “The Greasy Response to Virus Infections” Cell Host & Microbe, 13:375-7. PMC3654690

5. Lee B. (2013) Commentary, “Amping up PAMPs: another sensor for another PAMP” Proc Natl Acad Sci USA, 110:19183-4. PMC3845105

6. Lee B. (2018) Greasing the receptor. Nat Microbiol 3:1082-1083. doi: 10.1038/s41564-018-0251-2

7. Adelman ZN, Albritton LM, Boris-Lawrie K, Buchmeier MJ, Cannon P, Cho M, DiGiusto D, Donahue JK, Federoff HJ, Hammarskjold ML, Hardison AD, Hearing P, Lee B, Lee DA, Porteus MH, Ross LF, Ross SR, Wooley DP, Zoloth L.  (2018) Protect NIH's DNA advisory committee.  Science, 362:409-410.

Books

Lee B and Rota P (Editors). (2012) Henipavirus: Ecology, Molecular Virology, and Pathogenesis. Current Topics in Microbiology and Immunology, Vol 359.

Hardcover
ISBN 978-3-642-29818-9
$189.00
eBook
$149.99

Non-Peer Reviewed Publications

The Biology of Paramyxoviruses edited by Siba K. Samal
Reviewed by: Benhur Lee
The Quarterly Review of Biology, Vol 87, No. 4 (December 2012), p392
Published by: The University of Chicago Press
Article DOI: 10.1086/668141